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KMID : 0882419720150120031
Korean Journal of Medicine
1972 Volume.15 No. 12 p.31 ~ p.40
Clinical Study of Korean Hemorrhagic Fever
Koh Chang-Soon

Kim Won-Dong
Lee Jung-Sang
Lee Mun-Ho
Abstract
97 cases of Korean hemorrhagic fever who were admitted to Seoul National University Hospital from January 1965 to December 1971 were analysed on the standpoint of epidemiology, clinical symptoms and signs, laboratory findings and other routine studies.
The result were
1.The peak incidencewas on November and in the 4th decade. The male to female ratio was 3.8:1.
2. The most prevalent area was Yang Ju Goon, Kyung Gi Do. And the most susceptible occupation was farmer.
3. The mortality rate was 9.2%.
4. The most frequent clinical symptom was nausea, vomiting and abdominal pain. The most frequent clinical sign was fever, conjunctival injection and abdominal tenderness.
5. Laboratory findings
1) Hemoconcentration was seen in 36%, leukecytosis in 75%, albuminuria in 100¡Æo and hematuria in 81% of cases.
2) Delayed blood coagulation time was seen in 81%, platelet count below 209, 000/mm2 in 92% and positive Rumpel Leede test in 68%.
3) Serum Sodium level below 129 mEq/L was seen in 57%, serum Potassium, over 5.0 mEq/L in 45%, Calcium below-,9 mg% in 80% and Phosphorus over 4.5 mg% in 73%.
4) B U. N. level, over 40 mg% was seen in 93% and the cases whose B.U.N. level over 120 mg were seen more frequently in the groups whose platelet count below 10, 000/mm2.
5) The level of Lactic Dehydrogenase in oliguric phase was 1133¡¾357 ¥ì/ml and in, diuretic phase was 495.4¡¾166 ¥ì/ml.
6. The Renogram finding was either obstructive or tubular cell dysfunction pattern. 1
7.The most frequent chest X-ray -finding was pleural thickening and effusion.
8. Conservative trcctnient was done. Peritoneal dialysis in 7, cases and Hemodialysis in 10 cases were
done. The most frequent cause of death was infection & pulmonary edema.
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